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. 2018 Jun 5;9:566. doi: 10.3389/fphar.2018.00566

FIGURE 6.

FIGURE 6

Anti-inflammatory activities of S. aqueum leaf extract. (A) Effect of 1 h prior administration of S. aqueum (300 mg/kg, p.o.) or diclofenac (10 mg/kg, p.o.) on carrageenan (1% suspension, 0.1 ml/rat) induced-hind paw edema in rats. Edema thickness (mm) was measured before and then hourly for 6 h and at 24 h after carrageenan injection. Data represents the AUC0-24 and are expressed as mean ± SEM (n = 5–7). (B) Effect of carrageenan (500 μg, i.p.) on leukocytes migration into the peritoneal cavity (total number × 106) with or without 1 h prior treatment with the extract (300 mg/kg, p.o.) or diclofenac (10 mg/kg, p.o.). Data are expressed as mean. ± SEM (n = 5–7). ∗p < 0.01 vs. control values; #p < 0.05 vs. carrageenan.