Table 3.

Inhibition activities of the extract on LOX, COX-1, and COX-2 enzymes.

	IC50 (μg/mL)	IC50 (μg/mL)
Treatment	LOX	COX-1	COX-2	SI
S. aqueum extract	2.54 ± 0.19	7.11 ± 0.43	0.12 ± 0.005	59.3
Celecoxib	-	15.1 ± 0.72	0.049 ± 0.002	308.2
Diclofenac	2.11 ± 0.14	3.8 ± 0.17	0.84 ± 0.04	4.5
Indomethacin	-	0.041 ± 0.001	0.51 ± 0.02	0.08
Zileuton	3.51 ± 0.21	-	-	-

SI is COX selectivity index which is defined as IC₅₀ (COX-1)/IC₅₀ (COX-2).