Table 4.
5-HT and HCRT-1 concentration in MA, MO, both migraine patients (MA+MO) and controls.
| Controls | MA | MO | Migraine patients | p(I) | p(II) | |
|---|---|---|---|---|---|---|
| 5-HT | 0.095 ± 0.090; | 0.123 ± 0.0941,2; | 0.084 ± 0.086; | 0.098 ± 0.091; | 0.03081 | 0.03692 |
| [μg/mL] | 0.078; | 0.0121; | 0.068; | 0.073; | 0.3084 | |
| 0.029, 0.140 | 0.053, 0.170 | 0.018, 0.110 | 0.023, 0.151 | 0.7240 | ||
| HCRT-1 | 664.1 ± 406.0; | 648.1 ± 341.4; | 715.9 ± 358.9; | 684.4 ± 349.6; | 0.7273 | 0.9900 |
| [pg/mL] | 542.10; | 592.65; | 678.75; | 609.90; | 0.4779 | |
| 319.8, 1007.1 | 329.35, 962.28 | 384.88, 1058.88 | 357.85, 1033.53 | 0.6405 |
The values in each cell represent: mean ± standard deviation; median; quartile 1, and quartile 3. MA, migraine with aura, MO, migraine without aura, 5-HT, serotonin, HCRT-1, hypocretin-1. Kruskal-Wallis test (p I) and Mann-Whitney test (p II). Statistical significance at p < 0.05: 1between MA and MO (p I); 2between MA and controls (p II). Spearman’s coefficient, Rs = +0.4049, p = 0.010 between 5-HT and HCRT-1 in control group.