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. 2018 Jun 5;11:191. doi: 10.3389/fnmol.2018.00191

Table 5.

5-HT concentration in MA, MO, both migraine patients (MA+MO) and control subjects regarding different genotypes of 5-HTTLPR, HCRTR1 G1222A, and *G29A.

Controls MA MO Migraine patients p (I) p (II)
5-HTTLPR
SS 0.057 ± 0.053 0.165 ± 0.0351 0.086 ± 0.104 0.111 ± 0.095 0.03671 0.1519
SL 0.092 ± 0.098 0.122 ± 0.095 0.093 ± 0.076 0.106 ± 0.086 0.2049 0.1724
LL 0.106 ± 0.087 0.110 ± 0.104 0.072 ± 0.093 0.084 ± 0.097 0.0716 0.0951
HCRTR1 G1222A
GG 0.101 ± 0.102 0.140 ± 0.0572 0.074 ± 0.078 0.106 ± 0.075 0.03752 0.4233
GA 0.094 ± 0.085 0.130 ± 0.109 0.083 ± 0.094 0.098 ± 0.100 0.1298 0.8161
AA 0.083 ± 0.077 0.093 ± 0.095 0.091 ± 0.075 0.092 ± 0.083 0.8636 0.6301
HCRTR1 *G29A
GG 0.095 ± 0.089 0.137 ± 0.0943,4 0.084 ± 0.089 0.103 ± 0.094 0.00433,4 0.6078
GA 0.083 ± 0.111 0.062 ± 0.066 0.080 ± 0.064 0.070 ± 0.063 0.7965 0.8366

The values in each cell represent: mean ± standard deviation. MA, migraine with aura, MO, migraine without aura. Kruskal-Wallis test (p I) and Mann-Whitney test (p II). Statistical significance at p < 0.05:1between MA and controls (p I); 2between MA and MO (p I); Statistical significance at p < 0.01: 3between MA and controls, 4between MA and MO (p I).