Table 1.
Clinico-demographic correlations: anti-cN-1A in primary Sjögren’s syndrome (pSS).
| pSS | Anti-cN-1A positive 12% (23/193) | Anti-cN-1A negative 88% (170/193) | p-Value |
|---|---|---|---|
| Provenance of the serum | 0.21 | ||
| – Italy | 7% | 93% | |
| – The Netherlands | 8% | 92% | |
| – France | 19% | 81% | |
| – Sweden | 15% | 85% | |
| Female/male | 12%/18% | 88%/82% | 0.63 |
| Presence of muscular complaintsb | 33% (4/12) | 27% (20/74) | 0.80 |
| Presence of autoimmune co-morbidityc (number of patients) | 15% (3/20) | 5% (7/135) | 0.05a |
| – Antiphospholipid syndrome | – 4% (1) | – 0% (0) | |
| – Rheumatoid arthritis | – 4% (1) | – 2% (4) | |
| – Other | – 4% (1) | – 2% (3) | |
| Presence of current or past viral infectiond | 5% (1/19) | 3% (4/128) | 0.51 |
| Presence of other antibodies | |||
| – dsDNA | 0% (0/23) | 6% (11/170) | 0.37 |
| – anti-nucleosomes | 0% (0/23) | 6% (11/170) | 0.37 |
| – Ro52 | 65% (15/23) | 68% (115/170) | 0.82 |
aStatistically significant (p ≤ 0.05).
bMissing data in 55% of patients.
cMissing data in 20% of patients.
dMissing data in 24% of patients.