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. 2018 Jun 5;9:1200. doi: 10.3389/fimmu.2018.01200

Table 3.

Anti-cN-1A reactivity among systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) cohorts in former and current studies.

Cohort Technique Origin of samples Disease Number of patients Anti-cN-1A positivity (%)
Herbert et al. (4) ELISA with 3 synthetic peptides The Netherlands SLE 44 20
pSS 22 36

Kramp et al. (7) ELISA with recombinant full-length proteina North American SLE 33 6
pSS 20 0

Lloyd et al. (6) Immunoblotting against NT5C1A (full-length)-transfected and nontransfected HEK 293 cell lysates USA SLE 96 14
pSS 44 23

Muro et al. (5) ELISA with recombinant full-length protein Japan SLE 50 6
pSS 50 4

Rietveld et al. (current study) ELISA with recombinant full-length proteina Europe SLE 252 10
pSS 193 12

aThe same standardized ELISA was used in these studies.