Table 3.
Cohort | Technique | Origin of samples | Disease | Number of patients | Anti-cN-1A positivity (%) |
---|---|---|---|---|---|
Herbert et al. (4) | ELISA with 3 synthetic peptides | The Netherlands | SLE | 44 | 20 |
pSS | 22 | 36 | |||
Kramp et al. (7) | ELISA with recombinant full-length proteina | North American | SLE | 33 | 6 |
pSS | 20 | 0 | |||
Lloyd et al. (6) | Immunoblotting against NT5C1A (full-length)-transfected and nontransfected HEK 293 cell lysates | USA | SLE | 96 | 14 |
pSS | 44 | 23 | |||
Muro et al. (5) | ELISA with recombinant full-length protein | Japan | SLE | 50 | 6 |
pSS | 50 | 4 | |||
Rietveld et al. (current study) | ELISA with recombinant full-length proteina | Europe | SLE | 252 | 10 |
pSS | 193 | 12 |
aThe same standardized ELISA was used in these studies.