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. 2018 Jun 5;9:694. doi: 10.3389/fphys.2018.00694

FIGURE 4.

FIGURE 4

Sympathetic activity in tissues from control and CIH guinea pigs. (A) Superior cervical ganglion (SCG) endogenous content of norepinephrine (NE) and dopamine (DA) expressed as pmol/mg tissue in control and CIH measured by HPLC-ED. ∗∗∗p < 0.0001 CIH vs. C. Data are mean ± SEM (n = 14–16). Two-way ANOVA with Sidak’s multiple comparison test. (B) Renal artery (RA) endogenous NE levels expressed as pmol/mg tissue. Data are mean ± SEM (n = 6–7); Unpaired t-test. (C) Rate of 3H-NE synthesis expressed as pmol/mg tissue/h in RA. ∗p < 0.05 CIH vs. C. Data are mean ± SEM (n = 6–7); Unpaired t-test. (D) Adrenal medulla (AM) endogenous content of NE and epinephrine (E) expressed as nmol/mg tissue. Data are mean ± SEM (n = 14–16); Two-way ANOVA with Sidak’s multiple comparison test. (E) Plasma NE and (E) levels expressed as pmol/mL. ∗p < 0.05 CIH vs. C; Data are mean ± SEM (n = 6–8); Unpaired t-test. (F) Fasting glucose plasma levels expressed as mg/dL. ∗p < 0.05 CIH vs. C; Data are mean ± SEM (n = 16); Unpaired t-test.