Table 3.
Gene expression levels in fold change values determined by microarray analysis with at least three hits and a fold change ≥±1.5 over all time points independent of diet.
ID | Name | Trauma vs. Control | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Normal | Obese | ||||||||||
1 h | 6 h | 24 h | 3 days | 8 days | 1 h | 6 h | 24 h | 3 days | 8 days | ||
107765 | Ankrd1 | 1.60 | 14.26 | −5.81 | 50.36 | 13.48 | 2.69 | 4.38 | −2.79 | 1.15 | 1.91 |
11820 | App | 1.30 | 1.18 | −1.59 | 2.17 | 1.68 | 1.06 | −1.08 | −1.22 | 1.33 | 1.18 |
11829 | Aqp4 | −1.32 | −1.20 | 1.74 | −5.67 | −2.48 | −1.06 | −1.03 | 1.66 | −1.79 | −1.57 |
12051 | Bcl3 | 1.92 | 1.85 | 1.21 | 2.69 | 1.41 | 2.31 | 1.76 | 1.23 | 1.23 | −1.06 |
12226 | Btg1 | 1.66 | 1.42 | −1.14 | 1.89 | 1.53 | 1.67 | 1.56 | −1.18 | 1.33 | 1.29 |
12267 | C3ar1 | 2.01 | 1.79 | 2.14 | 32.56 | 4.19 | 1.30 | 1.96 | 3.03 | 5.98 | 1.72 |
12363 | Casp4 | 1.63 | 2.00 | 1.31 | 2.57 | 1.26 | 1.71 | 1.74 | 1.37 | 1.36 | 1.20 |
20305 | Ccl6 | 1.84 | 2.35 | 2.72 | 11.06 | 2.56 | −1.02 | 1.46 | 2.99 | 3.01 | 1.39 |
20307 | Ccl8 | 1.11 | 2.83 | 6.35 | 13.98 | 2.75 | −1.73 | 1.67 | 5.24 | 4.12 | 1.74 |
20308 | Ccl9 | 2.07 | 3.63 | 2.38 | 10.02 | 2.78 | 1.00 | 1.98 | 2.97 | 3.10 | 1.19 |
23833 | Cd52 | 1.80 | 2.14 | 2.15 | 14.45 | 2.95 | 1.64 | 1.45 | 2.85 | 2.69 | 2.13 |
12522 | Cd83 | 2.27 | 1.08 | −1.15 | 1.89 | 1.52 | 1.91 | 1.16 | 1.11 | 1.24 | 1.06 |
14962 | Cfb | 1.22 | 1.43 | 2.53 | 3.39 | 1.59 | −1.95 | 1.34 | 2.56 | 2.90 | 1.64 |
76722 | Ckmt2 | −1.02 | −1.00 | −1.63 | −2.45 | −1.38 | 1.12 | −1.03 | −1.51 | −1.63 | 1.15 |
29876 | Clic4 | 1.46 | 1.62 | −1.06 | 2.78 | 1.43 | 1.28 | 1.73 | 1.10 | 1.19 | 1.20 |
12825 | Col3a1 | 1.53 | 1.14 | 1.66 | 4.59 | 3.71 | −1.26 | 1.04 | 1.38 | 2.65 | 1.48 |
72042 | Cotl1 | 1.28 | 1.15 | 1.43 | 4.49 | 1.70 | 1.16 | 1.14 | 1.53 | 1.63 | 1.29 |
14219 | Ctgf | 2.35 | 2.35 | −1.96 | 3.70 | 1.36 | 1.91 | 1.92 | −1.15 | −1.15 | −1.09 |
13040 | Ctss | 1.96 | 1.80 | 2.11 | 32.07 | 4.17 | −1.10 | 1.48 | 3.21 | 6.13 | 3.59 |
16007 | Cyr61 | 2.47 | 1.91 | −2.06 | 2.11 | 1.35 | 2.90 | 1.97 | −1.55 | −1.30 | 1.05 |
72318 | Cyth4 | 1.35 | 1.42 | 1.37 | 6.71 | 1.96 | 1.08 | 1.27 | 1.67 | 2.18 | 1.27 |
13730 | Emp1 | 2.39 | 2.52 | −1.23 | 6.12 | 1.85 | 1.86 | 2.42 | 1.24 | 1.95 | 1.17 |
74155 | Errfi1 | 2.29 | 2.05 | −1.32 | 2.17 | 1.58 | 2.12 | 1.71 | 1.09 | −1.25 | −1.01 |
14130 | Fcgr2b | 1.63 | 1.72 | 1.71 | 11.10 | 2.43 | −1.23 | 1.35 | 1.81 | 2.49 | 1.37 |
14190 | Fgl2 | 2.46 | 2.98 | −1.09 | 2.86 | 1.05 | 2.76 | 3.20 | 1.17 | 1.23 | 1.47 |
14268 | Fn1 | 1.82 | 1.35 | 1.00 | 6.07 | 3.39 | −1.11 | 1.16 | 1.04 | 1.18 | 1.51 |
14545 | Gdap1 | −1.10 | −1.31 | −1.56 | −2.37 | −1.68 | −1.03 | −1.20 | 1.01 | −1.31 | 1.16 |
14955 | H19 | −1.08 | −1.06 | −1.54 | 2.05 | 2.71 | 1.18 | 1.17 | −1.82 | −1.47 | 1.53 |
15430 | Hoxd10 | −2.33 | −1.07 | 5.59 | −5.67 | −2.77 | −1.94 | −1.24 | 3.77 | 1.95 | −2.00 |
319415 | Hs3st5 | −1.09 | −1.44 | 1.01 | −2.53 | −1.94 | 1.07 | −1.51 | −1.14 | −1.06 | −1.17 |
15894 | Icam1 | 1.42 | 1.42 | 1.04 | 1.61 | 1.31 | 1.62 | 1.33 | 1.09 | 1.26 | 1.10 |
15959 | Ifit3 | −1.30 | 1.64 | 1.59 | 5.29 | 1.81 | −1.50 | 1.52 | 2.99 | 1.61 | 1.90 |
80719 | Igsf6 | 1.63 | 1.18 | 1.29 | 13.78 | 2.35 | 1.88 | 1.68 | 1.32 | 2.06 | 1.49 |
73914 | Irak3 | 1.65 | 1.58 | 1.09 | 1.92 | 1.38 | 1.24 | 1.41 | 1.08 | 1.18 | 1.15 |
16402 | Itga5 | 2.15 | 2.35 | 1.11 | 5.35 | 1.75 | 2.11 | 2.54 | 1.09 | 1.35 | −1.08 |
16414 | Itgb2 | 2.03 | 2.14 | 1.43 | 9.36 | 1.95 | 1.60 | 1.80 | 1.50 | 3.19 | 1.64 |
277396 | Klhl23 | 1.14 | −1.16 | −1.56 | −1.64 | −1.18 | 1.02 | −1.10 | −1.22 | −1.70 | −1.10 |
244864 | Layn | 1.02 | 1.60 | 1.13 | 3.13 | 1.63 | 1.01 | 1.44 | 1.17 | 1.53 | 1.09 |
18826 | Lcp1 | 2.36 | 2.10 | 1.56 | 14.25 | 2.97 | 2.03 | 1.94 | 2.01 | 3.93 | 2.00 |
16822 | Lcp2 | 1.90 | 1.91 | 1.47 | 5.60 | 1.88 | 1.61 | 1.76 | 1.45 | 2.04 | 1.29 |
16854 | Lgals3 | 1.42 | 1.95 | 1.82 | 19.07 | 3.85 | −1.11 | 1.49 | 2.76 | 5.87 | 1.34 |
56722 | Litaf | 1.55 | 1.94 | 1.06 | 3.73 | 1.31 | 1.98 | 1.85 | 1.34 | 1.53 | 1.11 |
16948 | Lox | 2.53 | 3.12 | −1.14 | 12.02 | 2.36 | 1.34 | 2.17 | 2.06 | 3.64 | 1.22 |
16979 | Lrrn1 | −1.38 | −1.44 | −3.01 | 5.06 | 2.49 | 1.90 | 1.20 | −1.13 | −2.47 | 1.05 |
26410 | Map3k8 | 1.69 | 2.59 | 1.09 | 1.74 | 1.18 | 2.32 | 2.23 | 1.04 | 1.19 | 1.01 |
59090 | Midn | 1.70 | 2.87 | 1.01 | 2.70 | 1.41 | 2.74 | 1.74 | −1.21 | −1.07 | 1.10 |
17476 | Mpeg1 | 2.10 | 1.76 | 1.61 | 31.46 | 5.10 | 1.33 | 2.63 | 2.54 | 6.09 | 3.55 |
73656 | Ms4a6c | 2.01 | 2.24 | 2.85 | 29.44 | 3.42 | −1.08 | 2.27 | 5.73 | 5.00 | 2.26 |
74843 | Mss51 | 1.75 | 1.94 | −5.13 | 3.62 | 3.14 | 1.28 | 1.07 | 1.02 | 1.14 | 1.87 |
17748 | Mt1 | 1.96 | 3.50 | 3.75 | 6.21 | 2.08 | 3.66 | 1.63 | 2.57 | 1.90 | −1.05 |
18198 | Musk | −1.20 | 1.10 | 1.70 | 3.69 | 2.99 | 1.06 | 1.39 | 1.68 | 1.60 | −1.15 |
17874 | Myd88 | 1.49 | 3.81 | 1.36 | 4.14 | 1.53 | 2.41 | 2.20 | 1.12 | 1.41 | 1.20 |
228785 | Mylk2 | 1.13 | 1.10 | −1.53 | −2.16 | −1.43 | 1.04 | 1.07 | −1.36 | −1.00 | 1.21 |
17937 | Nab2 | 1.13 | 1.77 | 1.11 | 2.28 | 1.49 | 1.66 | 2.05 | 1.18 | 1.07 | −1.07 |
105855 | Nckap1l | 1.63 | 1.36 | 1.22 | 12.33 | 2.06 | 1.15 | 1.47 | 1.62 | 2.89 | 1.26 |
18414 | Osmr | 1.57 | 2.13 | 1.09 | 2.89 | 1.22 | 1.41 | 2.08 | 1.27 | 1.21 | 1.04 |
67041 | Oxct1 | 1.03 | −1.12 | −1.59 | −2.25 | −1.55 | 1.10 | −1.02 | −1.58 | −1.46 | 1.10 |
170768 | Pfkfb3 | 1.51 | 1.20 | 1.11 | −3.78 | −2.43 | −1.11 | 1.45 | −1.21 | 1.75 | −1.11 |
66681 | Pgm1 | 1.57 | 1.81 | 1.09 | 3.22 | 1.19 | 1.91 | 1.60 | 1.06 | 1.08 | 1.15 |
83490 | Pik3ap1 | 1.26 | 1.12 | 1.15 | 4.09 | 1.57 | 1.04 | 1.31 | 1.68 | 2.27 | 1.15 |
234779 | Plcg2 | 1.21 | 1.09 | 1.11 | 2.09 | 1.22 | −1.08 | 1.13 | 1.31 | 1.53 | 1.18 |
67448 | Plxdc2 | 1.39 | −1.14 | −1.72 | 1.77 | 1.71 | 1.11 | −1.18 | −1.42 | 1.06 | 1.28 |
243382 | Ppm1k | 1.16 | −1.22 | −1.60 | −2.35 | −1.80 | 1.02 | −1.18 | −1.46 | −1.63 | 1.10 |
19264 | Ptprc | 2.73 | 1.59 | 1.29 | 8.35 | 1.95 | 1.83 | 1.70 | 1.67 | 2.19 | 1.93 |
67442 | Retsat | −1.12 | −1.27 | −1.52 | −1.78 | −1.33 | 1.09 | −1.14 | −1.77 | −1.12 | −1.08 |
74194 | Rnd3 | 1.84 | 1.32 | −1.13 | 1.82 | 1.51 | 1.50 | 1.62 | 1.09 | 1.07 | 1.05 |
672511 | Rnf213 | 1.11 | 1.54 | 1.60 | 4.13 | 1.44 | −1.10 | 1.59 | 1.95 | 2.03 | 1.29 |
20194 | S100a10 | 1.84 | 1.56 | 1.02 | 5.65 | 1.61 | 1.31 | 1.42 | 1.62 | 1.92 | 1.37 |
20970 | Sdc3 | 1.02 | 1.24 | 1.62 | 6.20 | 1.57 | −1.05 | 1.02 | 1.81 | 2.31 | 1.30 |
20345 | Selplg | 1.50 | 1.39 | 1.28 | 6.13 | 2.17 | 1.54 | 1.26 | 1.60 | 2.64 | 1.35 |
18787 | Serpine1 | 4.44 | 3.18 | 1.18 | 9.62 | 1.19 | 3.69 | 3.30 | 1.19 | 1.74 | 1.06 |
100217426 | Snord49b | −1.01 | 1.07 | 1.46 | 2.35 | 1.83 | 1.01 | −1.31 | 1.89 | 1.59 | 1.14 |
234214 | Sorbs2 | 1.07 | 1.12 | 1.09 | −2.63 | −1.98 | −1.02 | 1.14 | −1.07 | 1.52 | −1.07 |
98267 | Stk17b | 1.68 | 1.23 | −1.16 | 4.69 | 1.58 | 1.66 | 1.08 | −1.14 | 1.14 | 1.18 |
21825 | Thbs1 | 4.19 | 4.58 | −2.00 | 10.10 | 1.63 | 3.99 | 2.50 | 1.20 | 2.69 | −1.22 |
279572 | Tlr13 | 1.36 | 1.89 | 1.20 | 10.16 | 1.55 | 1.33 | 2.49 | 1.70 | 3.03 | 1.14 |
21923 | Tnc | 1.81 | 2.79 | −1.64 | 22.69 | 2.44 | 1.36 | 1.97 | 1.01 | 2.52 | −1.01 |
21933 | Tnfrsf10b | 1.31 | 1.39 | 1.24 | 2.05 | 1.07 | 1.63 | 1.62 | 1.10 | 1.11 | 1.03 |
69480 | Ttc9 | 1.03 | 1.52 | −1.66 | 6.89 | 6.18 | 1.21 | 1.90 | −1.19 | −1.42 | 1.28 |
22235 | Ugdh | 3.18 | 1.56 | 1.03 | 2.85 | 1.58 | 2.32 | 1.58 | 1.02 | 1.26 | 1.11 |
381066 | Zfp948 | 1.57 | 1.28 | 1.03 | 1.93 | 1.34 | 1.76 | 1.92 | 1.07 | 1.15 | 1.06 |
Red = significantly upregulated, green = significantly downregulated. Significance level is p ≤ 0.05. Log2 values were converted to fold change, and subsequently if value < 1 inverted to get negative values, thus baseline = ± 1. For corresponding significance levels, see Supplementary Table 3.