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(A) Schematic of the ultrasensitive pH-triggered charge/size dual-rebound gene delivery system for efficient antitumor applications. (B) Fast hydrodynamic charge/size dual-rebound property and (C) TEM of the gene delivery system. (GP)D and P[(GP)D] represent (PLG/PEI)/DNA and PEG[(PLG/PEI)/DNA], respectively. Reproduced with permission from 184, copyright 2016 American Chemical Society.
