Table 3.

Biodistribution of ¹¹¹In-LipoDox 24 h after intravenous injection in CT26 tumor-bearing mice. Values are presented as percentage of injected dose per gram (%ID/g; mean ± standard error of the mean; N= 3 at each time point).

Organ	Naïve	αPEG antibody PT	Endogenous αPEG
Blood	19.14 ± 2.11	0.84 ± 0.25	1.22 ± 0.16
Tumor	25.02 ± 7.08	8.97 ± 2.96	4.08 ± 0.55
Spleen	31.49 ± 3.37	72.45 ± 27.16	88.75 ± 16.51
Liver	10.60 ± 1.00	11.82 ± 0.80	11.67 ± 0.87
SI	28.16 ± 5.74	6.91 ± 1.52	2.03 ± 0.66
LI	3.44 ± 0.97	1.20 ± 0.43	0.93 ± 0.31
Muscle	0.68 ± 0.27	1.16 ± 1.28	0.52 ± 0.07
Bone	0.76 ± 0.49	0.73 ± 0.31	0.33 ± 0.14
Marrow	18.76 ± 24.22	5.60 ± 5.57	32.07 ± 20.21
Bladder	1.78 ± 0.67	1.47 ± 0.85	1.52 ± 0.72
Kidney	8.47 ± 1.54	5.08 ± 0.56	4.10 ± 0.33
Urine	1.12 ± 0.32	2.32 ± 0.13	1.56 ± 1.37
Feces	0.34 ± 0.15	1.03 ± 0.37	1.08 ± 0.72

SI: small intestine; LI: large intestine