Fig. 2.

The latency to abnormal electrographic activity was dissociated from the latency to behavioral signs following the administration of DFP (A), sarin (B) or VX (C). Although toxic signs that included convulsive-like behaviors began within minutes of NA or DFP administration, the first electrographic signs of seizure activity sometimes did not occur until an hour or more following the administration of one of the OPs. The shaded area on each graph represents the time within which toxic signs appeared. Rats that survived for more than 15 min had either SE (●) or epileptiform activity (▲, EA). Some animals died within 15 min after DFP administration, but exhibited abnormal electrographic activity before death (○, SE; △; EA).