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. 2018 May 29;2018:1676851. doi: 10.1155/2018/1676851

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Copyright © 2018 Roxana-Maria Amărandi et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Biosensors for potency assay simplification. Traditional potency assay measurement technologies include (a) Protein expression via Sodium Dodecyl Sulphate-PolyAcrylamide Gel Electrophoresis (SDS-PAGE), (b) Gene expression via quantitative Real Time Polymerase Chain Reaction (qRT-PCR), (c) Live cell flow cytometry via Fluorescence-Activated Cell Sorting (FACS) analysis, or (d) Enzyme-Linked Immunosorbent Assay (ELISA) for antibody targets. These are typically multistep procedures requiring more time and expertise than needed for application of (e) dedicated biosensors tailored for specific target analytes.