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The effects of HGT on IL-12 and STAT4 expression in mice. (a) Immunohistochemistry of IL-12 in joints of mice with the treatment of HGT; (b) the levels of IL-12 mRNA in mouse joints after the treatment of HGT; (c) the expression of IL-12Rβ1 and STAT4 protein in CIA mice joints; (d) IL-12 in serum of CIA mice with the treatment of HGT. The data are represented as the mean ± SD (n = 7); ∗∗ p < 0.01, when compared with the model group.
