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. 2018 Jun 11;19:115. doi: 10.1186/s12931-018-0819-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The overexpression of hsa_circ_0046264 promoted BRCA2 expression and cancer cell invasion. a The overexpression of hsa_circ_0046264 and the suppression of miR-1245 promoted BRCA2 expression. The simultaneous transfection of hsa_circ_0046264 and miR-1245 did not result in significant change of BRCA2 expression. ^*P < 0.05, compared with control group. ^#P < 0.05, compared with circ264 group. b The overexpression of hsa_circ_0046264 and the suppression of miR-1245 promoted cell invasion. The simultaneous transfection of hsa_circ_0046264 and miR-1245 did not result in significant change of cell invasion. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, compared with control group. ^#P < 0.05, compared with circ264 group