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. 2018 Jun 11;19:115. doi: 10.1186/s12931-018-0819-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Hsa_circ_0046264 overexpression suppressed lung cancer development in vitro. a-b Cell viability of A549 and 95-D cells decreased in circ264 group and antimir1245 group but increased in sicirc groups and mir1245 group tested by CCK8 assay. ^*P < 0.05, compared with control group. c-d Apoptosis of A549 and 95-D cells was promoted in circ264 group and antimir1245 group but inhibited in sicirc groups and mir1245 group. ^*P < 0.05, compared with control group