BM-MSCs reduce LPS-induced ALI. (A) LIS. Compared with controls, ALI rats exhibited significantly increased LIS. In contrast, BM-MSC rats exhibited decreased LIS compared with that of LPS. (B) The total cell count and (C) neutrophil percentage in the bronchoalveolar lavage fluid. Compared with the controls, ALI rats exhibited significantly increased total cell count (P<0.05) and neutrophil percentage (P<0.05). The BM-MSC group exhibited decreased neutrophil percentage compared with the LPS group (P<0.05). *P<0.05 vs. control; #P<0.05 vs. LPS. BM, bone marrow-derived; MSC, mesenchymal stem cell; LIS, lung injury score; ALI, acute lung injury; LPS, lipopolysaccharide.