Table I.

miRNAs implicated in rats with ALI.

miRNA name	Fold-Regulation	change direction	P-value
rno-miR-760-3p	3.7	Up	0.030
rno-miR-223-3p	2.9	Up	0.048
rno-miR-449c-3p	2.1	Up	0.040
rno-miR-503-3p	2.1	Up	0.045
rno-miR-142-3p	2.0	Up	0.047
rno-miR-100-5p	2.4	Down	0.020
rno-miR-199a-5p	2.3	Down	0.030
rno-miR-99a-5p	2.3	Down	0.010
rno-miR-199a-3p	2.2	Down	0.030
rno-miR-181a-5p	2.1	Down	0.040
rno-miR-497-5p	2.1	Down	0.030
rno-miR-191a-5p	2.1	Down	0.010
rno-miR-28-5p	2.0	Down	0.030
rno-miR-3065-5p	2.0	Down	0.040
rno-miR-196b-3p	2.0	Down	0.046

miRNAs listed were significantly upregulated or downregulated in the lung tissue of rats with ALI compared with saline-treated controls, with P<0.05 and a fold-change ≥2. miRNA/miR, microRNA; ALI, acute lung injury; rno, Rattus norvegicus.