Table II.
Altered miRNAs in rats with ALI following BM-MSC treatment.
| miRNA name | Fold-Regulation | change direction | P-value |
|---|---|---|---|
| rno-miR-1843-3p | 4.5 | Up | 0.013 |
| rno-miR-323-3p | 3.8 | Up | 0.015 |
| rno-miR-183-5p | 3.7 | Up | 0.048 |
| rno-miR-182 | 2.9 | Up | 0.015 |
| rno-miR-196b-3p | 2.5 | Up | 0.043 |
| rno-miR-547-3p | 2.0 | Down | 0.010 |
| rno-miR-301b-5p | 2.1 | Down | 0.045 |
| rno-miR-503-3p | 2.0 | Down | 0.048 |
| rno-miR-142-3p | 2.0 | Down | 0.049 |
miRNAs listed were significantly upregulated or downregulated in the lung tissue of BM-MSC-treated rats with ALI compared with saline-treated controls, with P<0.05 and a fold-change ≥2. miRNA/miR, microRNA; ALI, acute lung injury; BM-MSC, bone marrow-derived mesenchymal stem cells; rno, Rattus norvegicus.