Skip to main content
. Author manuscript; available in PMC: 2018 Jun 12.
Published in final edited form as: Bioconjug Chem. 2018 Jan 17;29(2):296–305. doi: 10.1021/acs.bioconjchem.7b00622

Figure 6.

Figure 6

Inhibition of CXCR4 and cancer cell invasion. (a) CXCR4 inhibition of polyplexes and conjugate polyplexes in U2OS cells. AMD3100 (300nM) was used as a positive control. Data are shown as mean % CXCR4 antagonism relative to AMD3100 ± SD (n = 3). (b) Inhibition of cancer cell invasion. U2OS cells were treated with polyplexes or conjugate polyplexes (rPAMD 2.0 μg/mL) and allowed to invade through Matrigel upon stimulation with SDF-1 for 16 h. AMD3100 (300 nM) was used as positive control. Data are shown as mean number of invaded cells ± SD (n = 3).