Table 1. An overview of the Gene Groups in FlyBase release FB2017_02.
To provide a summary, the Gene Groups have been divided into major biological themes. The number of genes for each theme is shown, together with a small selection of example Gene Groups. Note, as some genes belong to more than one group, the number of genes for each theme does not represent the number of unique genes. There are 3789 unique genes within the Gene Group collection (FB2017_02).
| Themes | Number of Genes/Theme | Example Gene Groups |
|---|---|---|
|
| ||
| Gene Expression | 1227 | GENERAL TRANSCRIPTION FACTORS |
| RIBOSOMAL PROTEINS | ||
| SPLICEOSOMAL COMPLEXES | ||
| TRANSFER RNAS | ||
| TRANSLATION FACTORS | ||
|
| ||
| Post-Translational Modification | 919 | PROTEIN KINASES |
| PROTEIN PHOSOPHATASES | ||
| RING FINGER DOMAIN PROTEINS | ||
| UBIQUITINATION ENZYMES | ||
|
| ||
| Receptor & Receptor Signaling | 395 | CHEMORECEPTORS |
| G PROTEIN COUPLED RECEPTORS | ||
| NEUROPEPTIDES | ||
| ODORANT BINDING PROTEINS | ||
|
| ||
| Metabolism | 404 | GLUTATHIONE S-TRANSFERASES |
| OXIDATIVE PHOSPHORYLATION COMPLEXES | ||
| PROTEASOME SUBUNITS | ||
|
| ||
| Transmembrane Transport | 326 | ATP-BINDING CASSETTE TRANSPORTER-LIKE |
| ION CHANNELS | ||
| NUCLEAR PORE COMPLEX | ||
| VACUOLAR ATPASE SUBUNITS | ||
|
| ||
| Intracellular Transport | 217 | BLOC COMPLEXES |
| INTRACELLULAR TRANSPORT GROUPS | ||
| SNAREs | ||
| TETHERING FACTORS | ||
|
| ||
| Small GTPase Signaling | 201 | RAS GTPASE SUPERAMILY |
| RAS SUPERFAMILY GAPs | ||
| RAS SUPERFAMILY GEFs | ||
|
| ||
| Chromatin Organization | 191 | CHROMATIN MODIFYING COMPLEXES |
| CHROMATIN REMODELING COMPLEXES | ||
| POLYCOMB GROUP COMPLEXES | ||
| SMC COMPLEXES | ||
|
| ||
| Cytoskeletal | 180 | ACTINS |
| DYNEIN SUBUNITS | ||
| KINESINS | ||
| MYOSINS | ||
| TUBULINS | ||
|
| ||
| Cell-Cell Communication & Adhesion | 86 | BEAT, SIDE FAMILIES |
| CADHERINS | ||
| INTEGRINS | ||
|
| ||
| Apoptosis & Autophagy | 52 | AUTOPHAGY-RELATED COMPLEXES |
| AUTOPHAGY-RELATED GENES | ||
| CASPASES | ||
|
| ||
| Cell Cycle | 30 | ANAPHASE-PROMOTING COMPLEX |
| CHROMOSOMAL PASSENGER COMPLEX | ||
| ORIGIN RECOGNITION COMPLEX | ||
|
| ||
| Immunity | 30 | DROSOMYCINS |
| NIMROD GENES | ||
| PEPTIDOGLYCAN RECOGNITION PROTEINS | ||
|
| ||
| Other | 108 | HEAT SHOCK PROTEINS |
| TETRASPANINS | ||