Table 5.
Relationship of SNP of IL-1β gene with clinical characteristics in male with HCC.
| rs3917356 | OR (95% CI) | p | |||
|---|---|---|---|---|---|
| G/G+G/A | A/A | ||||
| Albumin (g/dL) | <3.5 | 43 (64.2) | 24 (35.8) | 1 | 0.97 |
| ≥3.5 | 53 (63.9) | 30 (36.1) | 1.01 (0.52–1.98) | ||
| AST (U/L) | 65.5 | 44 (63.8) | 25 (36.2) | 1 | 0.71 |
| ≥65.5 | 52 (66.7) | 26 (33.3) | 0.88 (0.45–1.74) | ||
| ALT (U/L) | <40 | 44 (62.0) | 27 (38.0) | 1 | 0.62 |
| ≥40 | 52 (65.8) | 27 (34.2) | 0.85 (0.43–1.65) | ||
| PVT | Negative | 68 (70.8) | 28 (29.2) | 1 | 0.029 |
| Positive | 28 (52.8) | 25 (47.2) | 2.17 (1.08–1.35) | ||
| Stage | I + II | 31 (62.0) | 19 (38.0) | 1 | 0.75 |
| III + IV | 64 (64.6) | 35 (35.4) | 0.89 (0.44–1.80) | ||
| Metastasis | Yes | 85 (67.5) | 41 (32.5) | 1 | 0.032 |
| No | 10 (43.5) | 13 (56.5) | 2.70 (1.09–6.67) | ||
| Cause | Hepatitis | 78 (62.4) | 47 (37.6) | 1 | 0.51 |
| Alcohol | 14 (70.0) | 6 (30.0) | 0.71 (0.26–1.87) | ||
| Size (cm) | <5 | 50 (61.7) | 31 (38.3) | 1 | 0.49 |
| ≥5 | 45 (67.2) | 22 (32.8) | 0.79 (0.40–1.56) | ||
Variables are shown as frequency (percentage). Albumin, AST, and ALT are divided by median value. Odds ratio (OR), 95% confidence interval (CI), and p-values were from logistic regression analysis controlling age as covariates.