Figure 5.

HSF2 promoted the expression of ALG3 and increased the proliferation, migration, and invasion ability of breast cancer cells. (A) The ChIP assay confirmed that HSF2 was bound to the ALG3 promoter. (B) Silencing HSF2 inhibited the expression of ALG3. (C) Overexpression of HSF2 increased the expression of ALG3. (D) Cellar proliferation was detected by CCK-8. (E, F) Breast cancer MCF-7 cell migration ability was detected by the wound healing assay. (G, H) Breast cancer MCF-7 cell invasion ability was detected by Matrigel invasion assays.