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. 2016 Jul;57(8):3685–3697. doi: 10.1167/iovs.16-19105

Figure 6.

Figure 6

Immunohistochemical analysis of FGFR2 expression in KC and normal corneal sections. (A) An overlay of both anti-FGFR2 (red) and nuclear stain (blue) in normal corneal section. (B) An overlay of both anti-FGFR2 (red) and nuclear stain (blue) in KC corneal section. (C) Fibroblast growth factor receptor 2 expression in keratocytes differentiated from iPSC. (C) Overlay of both anti-FGFR2 (red) and nuclear stain (blue) in keratocytes differentiated from normal corneal iPSC. (D) Same overlay as in (C) but in keratocytes differentiated from KC iPSC. (E) Fibroblast growth factor receptor 2 expression in iPSC-derived keratocytes and quantified by ImageJ from both normal and KC (n = 22). Fibroblast growth factor receptor 2 expression was downregulated by approximately 2-fold.