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. 2018 Apr 25;9:413. doi: 10.3389/fphar.2018.00413

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Copyright © 2018 Helma, Vorgrimmler, Gebele, Gütlein, Engeli, Zarn, Schilter and Lo Piparo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of experimental with predicted LOAEL values. Each vertical line represents a compound, dots are individual measurements (blue), predictions (green), or predictions far from the applicability domain, i.e., with warnings (red).