Table 5.
Balanced accuracies [%] using different subsets of the data sources for all possible two-class classification problems.
| Feature set | CN vs. AD | CN vs. FTLD | CN vs. DLB | CN vs. VaD | AD vs. FTLD | AD vs. DLB | AD vs. VaD | FTLD vs. DLB | FTLD vs. VaD | DLB vs. VaD |
|---|---|---|---|---|---|---|---|---|---|---|
| NP | 96.3 | 87.8 | 96.0 | 94.1 | 74.4 | 78.4 | 77.6 | 74.7 | 73.9 | 65.3 |
| CSF | 87.6 | 62.5 | 60.5 | 64.8 | 79.1 | 79.4 | 75.4 | 58.1 | 66.5 | 51.6 |
| VMRI | 81.3 | 83.7 | 75.4 | 90.8 | 61.4 | 62.0 | 90.7 | 72.6 | 87.2 | 91.6 |
| AMRI | 91.1 | 89.6 | 79.2 | 96.2 | 80.3 | 71.9 | 94.3 | 80.7 | 95.2 | 95.8 |
| NP and CSF | 97.2 | 85.7 | 95.5 | 93.7 | 80.6 | 85.2 | 84.0 | 74.2 | 74.5 | 57.9 |
| NP and VMRI | 97.2 | 91.7 | 94.0 | 96.6 | 75.3 | 81.5 | 93.1 | 80.7 | 89.9 | 86.3 |
| NP and AMRI | 97.4 | 96.1 | 92.4 | 99.6 | 82.7 | 75.9 | 95.9 | 85.5 | 95.2 | 93.7 |
| CSF and VMRI | 91.6 | 86.8 | 74.1 | 90.8 | 80.4 | 78.8 | 92.5 | 75.2 | 89.3 | 89.5 |
| CSF and AMRI | 92.2 | 90.9 | 79.2 | 96.2 | 84.4 | 74.7 | 94.8 | 81.2 | 95.2 | 95.8 |
| VMRI and AMRI | 89.8 | 88.6 | 83.0 | 96.6 | 81.0 | 72.1 | 94.3 | 80.7 | 92.6 | 95.8 |
| NP, CSF, and VMRI | 96.5 | 91.8 | 93.0 | 97.5 | 84.0 | 85.4 | 91.5 | 80.1 | 89.9 | 86.3 |
| NP, CSF, and AMRI | 97.4 | 93.0 | 93.4 | 97.9 | 88.0 | 80.4 | 98.0 | 85.5 | 93.1 | 93.7 |
| NP, VMRI, and AMRI | 95.0 | 93.1 | 92.8 | 97.1 | 83.4 | 76.3 | 95.2 | 86.5 | 92.6 | 95.8 |
| CSF, VMRI, and AMRI | 91.5 | 90.4 | 82.4 | 96.6 | 81.1 | 78.2 | 94.3 | 82.3 | 92.6 | 95.8 |
| All | 96.8 | 92.1 | 92.4 | 97.1 | 87.2 | 79.9 | 95.5 | 86.5 | 93.1 | 95.8 |
NP, neuropsychological tests; CSF, cerebrospinal fluid based biomarkers; VMRI, visual MRI ratings; AMRI, automatic MRI quantifications; CN, control.