Table 3.
NC | SD-aMCI | MD-aMCI | F-value | P-value | |
---|---|---|---|---|---|
Bi-hemispheric functional connectivity | |||||
Middle temporal gyrus | 0.48 ± 0.26 | 0.48 ± 0.17 | 0.28 ± 0.23 | 8.93 | <0.001bc |
Precuneus | 1.23 ± 0.26 | 1.21 ± 0.17 | 1.02 ± 0.24 | 10.92 | <0.001bc |
Postcentral gyrus | 0.54 ± 0.22 | 0.60 ± 0.18 | 0.37 ± 0.20 | 12.86 | <0.001bc |
Calcarine gyrus | 1.25 ± 0.24 | 1.33 ± 0.20 | 1.06 ± 0.20 | 8.71 | <0.001bc |
Cerebral metabolism | |||||
L Middle temporal gyrus | 1.26 ± 0.12 | 1.14 ± 0.14 | 1.11 ± 0.16 | 11.72 | <0.001ab |
R Middle temporal gyrus | 1.31 ± 0.14 | 1.22 ± 0.14 | 1.20 ± 0.15 | 6.94 | <0.001ab |
L Precuneus | 1.55 ± 0.15 | 1.50 ± 0.20 | 1.39 ± 0.13 | 9.50 | <0.001bc |
L Inferior parietal lobe | 1.42 ± 0.13 | 1.37 ± 0.13 | 1.26 ± 0.16 | 13.32 | <0.001bc |
R Inferior parietal lobe | 1.48 ± 0.12 | 1.40 ± 0.16 | 1.34 ± 0.17 | 8.05 | <0.001b |
CC subregions volume | |||||
CC-A | 771.08 ± 113.95 | 781.06 ± 183.62 | 756.16 ± 120.71 | 0.26 | 0.77 |
CC-AP | 374.65 ± 62.76 | 380.88 ± 87.48 | 343.75 ± 65.36 | 2.59 | 0.08 |
CC-C | 367.82 ± 63.85 | 356.59 ± 77.61 | 337.59 ± 59.22 | 1.98 | 0.14 |
CC-MP | 338.27 ± 61.17 | 342.06 ± 75.19 | 303.84 ± 56.78 | 3.61 | 0.03∗ |
CC-P | 921.65 ± 121.69 | 921.34 ± 157.03 | 904.50 ± 149.93 | 0.17 | 0.85 |
aPost hoc paired comparisons showed significant group differences between NC and SD-aMCI, after Bonferroni correction (p < 0.05). bPost hoc paired comparisons showed significant group differences between NC and MD-aMCI, after Bonferroni correction (p < 0.05). cPost hoc paired comparisons showed significant group differences between SD-aMCI and MD-aMCI, after Bonferroni correction (p < 0.05). ∗Post hoc paired comparisons showed significant group differences between NC and MD-aMCI as well as SD-aMCI and MD-aMCI, corrected by the LSD (p < 0.05). Data are presented as means ± SD. CC, corpus callosum; A, anterior; MA, mid-anterior; C, central; MP, mid-posterior; P, posterior.