Table 1.
This table summarizes which studies each of the fifteen goats completed. Abbreviations are as follow: u denotes unilateral dialysis, b denotes bilateral dialysis, L and R denote dialysis on the left and right side respectively, and mCSF denotes mock cerebral spinal fluid.
| DRUG | Goat 1 |
Goat 2 |
Goat 3 |
Goat 4 |
Goat 5 |
Goat 6 |
Goat 7 |
Goat 8 |
Goat 9 |
Goat 10 |
Goat 11 |
Goat 12 |
Goat 13 |
Goat 14 |
Goat 15 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DAY | mCSF | u (R) | u (L) | u (L) | u (L) | u (R) | u (L) | u (L × 2) |
b | b | b | b | b | b | ||
| 10uM DAMGO |
u (L) | u (R) | u (L) | u (L) | u (L) | u (R) | u (L) | u (L) | ||||||||
| 50uM DAMGO |
u (L) | u (R) | u (L) | u (L) | u (L) | u (R) | u (L) | u (L) | ||||||||
| 100uM DAMGO |
u (L&R) |
u (R) | u (L & R) |
u (L) | u (L & R) |
u (R) | u (L) & b |
u (R) | u (L) | b | b | b | b | b | b | |
| 0.5mM MUSCIMOL |
u (R) | u (L) | u (R) | u (R) | u (R) | u (L) | u (L) | |||||||||
| 1.0mM MUSCIMOL |
u (R) | u (L) | u (L) | u (R) | u (R) | u (L) | u (L) | |||||||||
| 10.0mM MUSCIMOL |
u (R) | u (L & R) |
u (L) | u (R) | u (R) | u (L) | u (L) | u (L) | ||||||||
| NIGHT | 100uM DAMGO |
u (L&R) |
u (R) | u (L) | u (L) | u | u (R) | u (L) & b |
u (L) | b | b | b | b | b × 2 | b |