Table 2.

Prognostic discrimination of the Recurrence Score assessment within patient subsets defined by clinico-pathological factors: Kaplan-Meier estimates for the 10-year proportions of event-free for disease-free survival (DFS), distant recurrence-free interval (DRFI), overall survival (OS), and breast cancer-specific survival (BCSS): NSABP B-28

	10-Year DFS (%)			P	10-Year DRFI (%)			P	10-Year OS (%)			P	10-Year BCSS (%)			P
	Risk Group				Risk Group				Risk Group				Risk Group
	Low	Inter	High		Low	Inter	High		Low	Inter	High		Low	Inter	High
Treatment
AC	75.5	53.4	45.3	<.001	80.8	62.5	53.2	<.001	91.5	69.9	60.7	<.001	94.2	75.3	67.9	<.001
AC-P	76.1	60.4	50.5	<.001	80.9	67.3	58.2	<.001	88.5	79.3	65.3	<.001	95.7	82.4	68.6	<.001
Surgery
Lumpectomy	80.0	63.3	53.5	<.001	84.0	71.7	60.6	<.001	92.3	81.0	71.3	<.001	96.4	83.8	74.1	<.001
Mastectomy	72.3	51.6	44.5	<.001	78.2	59.0	52.7	<.001	88.0	69.4	58.0	<.001	93.8	74.8	64.6	<.001
# of Positive Nodes
1–3	79.8	64.8	57.0	<.001	84.7	71.5	63.1	<.001	93.3	79.2	70.7	<.001	98.0	82.9	75.6	<.001
≥4	66.7	40.3	31.1	<.001	71.8	50.7	41.3	<.001	82.4	65.2	48.5	<.001	88.1	70.3	54.0	<.001
Age, y
< 50	78.2	57.8	52.1	<.001	83.4	65.5	57.9	<.001	91.9	74.7	68.9	<.001	95.2	75.7	72.7	<.001
≥ 50	74.0	56.3	42.2	<.001	79.0	64.4	52.8	<.001	88.7	74.8	54.7	<.001	94.8	82.0	61.8	<.001
Tumor size
≤ 2cm	76.5	65.4	65.1	0.08	81.6	72.0	69.4	0.03	89.2	79.8	77.2	0.01	96.2	83.0	82.0	<.001
> 2cm	74.7	49.2	38.3	<.001	79.8	58.3	47.8	<.001	90.6	70.1	55.1	<.001	93.7	75.1	60.5	<.001