Table 2.

The primary endpoint and its individual components in 1181 asymptomatic patients in a comparison of the two treatment groups in the CREST study [15]

Endpoint		Periprocedural period					4-year period (including periprocedural period)
	CAS	CEA	Absolute treatment effect of CAS vs. CEA (95% CI)	Hazard ratio for CAS vs. CEA (95% CI)	P-value	CAS	CEA	Absolute treatment effect of CAS vs. CEA (95% CI)	Hazard ratio for CAS vs. CEA (95% CI)	P-value
	Number of patients (%±SE)		Percentage points			Number of patients (%±SE)		Percentage points
Myocardial infarction
Asymptomatic patients	7 (1.2 ± 0.4)	13 (2.2 ± 0.6)	−1.0 (−2.5–0.4)	0.55 (0.22–1.38)	0.20	–	–	–	–	–
Any periprocedural stroke or postprocedural ipsilateral stroke
Asymptomatic patients	15 (2.5 ± 0.6)	8 (1.4 ± 0.5)	1.2 (−0.4–2.7)	1.88 (0.79–4.42)	0.15	24 (4.5 ± 0.9)	13 (2.7 ± 0.8)	1.9 (−0.5–4.3)	1.86 (0.95–3.66)	0.07
Any periprocedural stroke or death or postprocedural ipsilateral stroke
Asymptomatic patients	15 (2.5 ± 0.6)	8 (1.4 ± 0.5)	1.2 (−0.4–2.7)	1.88 (0.79–4.42)	0.15	24 (4.5 ± 0.9)	13 (2.7 ± 0.8)	1.9 (−0.5–4.3)	1.86 (0.95–3.66)	0.07
Primary endpoint (periprocedural stroke, myocardial infarction, or death, or ipsilateral stroke)
Asymptomatic patients	21 (3.5 ± 0.8)	21 (3.6 ± 0.8)	0.0 (−2.2–2.1)	1.02 (0.55–1.86)	0.96	30 (5.6 ± 1.0)	26 (4.9 ± 1.0)	0.7 (−2.1–3.4)	1.17 (0.69–1.98)	0.56

CAS carotid artery stenting, CEA carotid endarterectomy, CI confidence interval