Table 3.
Results of the forward multiple regression analyses assessing the relationship between calculated parameters and hypertensive disorder of pregnancy (PE, GH or CH, each in the separate model) after adjustment for factors potentially influencing F metabolism
| PE | GH | CH | |
|---|---|---|---|
| UFF/UFE | R = −0.516; p < 0.001 | R = −0.271; p = 0.004 | NS |
| THFstot/THEstot | R = 0.198; p = 0.045 | NS | NS |
| THFfree/THEfree | R = −0.214; p = 0.034 | NS | NS |
| alloTHFtot/Ftot | R = 0.338; p < 0.001 | NS | NS |
| THFtot/Ftot | R = 0.424; p < 0.001 | R = 0.233; p = 0.013 | NS |
| alloTHFtot/THFtot | NS | NS | R = −0.252; p = 0.028 |
| plasma F/E | R = −0.473; p < 0.001 | NS | NS |
| urinary Ftot/Etot | NS | NS | NS |
| THFstot + THEstot [µg/mmol Cr] | NS | R = 0.265; p = 0.007 | NS |
| THFstot/UFF | R = 0.424; p < 0.001 | R = 0.430; p < 0.001 | NS |
| (THFstot + THEstot)/UFF | R = 0.484; p < 0.001 | R = 0.342; p < 0.001 | NS |
| (THFstot + THEstot)/(UFF + UFE) | R = 0.342; p < 0.001 | R = 0.206; p = 0.029 | NS |
| F conjugation degree [%] | R = 0.467; p < 0.001 | R = 0.236; p = 0.010 | NS |
| E conjugation degree [%] | NS | NS | NS |
| THF conjugation degree [%] | R = 0.242; p = 0.019 | R = 0.246; p = 0.013 | NS |
| THE conjugation degree [%] | R = −0.233; p = 0.019 | NS | NS |
Each time, a semi-partial correlation (R) and a p-value were noted. The associations where the sole predictor of the response variable was the hypertensive disorder of pregnancy are marked in bold
UFF urinary free cortisol, UFE urinary free cortisone, THF tetrahydrocortisol, THE tetrahydrocortisone, alloTHF allo-tetrahydrocortisol, alloTHE allo-tetrahydrocortisone, NS not significant