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. 2018 Apr 2;61(1):125–133. doi: 10.1007/s12020-018-1586-4

Table 3.

Results of the forward multiple regression analyses assessing the relationship between calculated parameters and hypertensive disorder of pregnancy (PE, GH or CH, each in the separate model) after adjustment for factors potentially influencing F metabolism

PE GH CH
UFF/UFE R=−0.516; p < 0.001 R = 0.271; p = 0.004 NS
THFstot/THEstot R = 0.198; p = 0.045 NS NS
THFfree/THEfree R = −0.214; p = 0.034 NS NS
alloTHFtot/Ftot R = 0.338; p < 0.001 NS NS
THFtot/Ftot R = 0.424; p < 0.001 R = 0.233; p = 0.013 NS
alloTHFtot/THFtot NS NS R = −0.252; p = 0.028
plasma F/E R = −0.473; p < 0.001 NS NS
urinary Ftot/Etot NS NS NS
THFstot + THEstot [µg/mmol Cr] NS R = 0.265; p = 0.007 NS
THFstot/UFF R = 0.424; p < 0.001 R = 0.430; p < 0.001 NS
(THFstot + THEstot)/UFF R = 0.484; p < 0.001 R = 0.342; p < 0.001 NS
(THFstot + THEstot)/(UFF + UFE) R = 0.342; p < 0.001 R = 0.206; p = 0.029 NS
F conjugation degree [%] R = 0.467; p < 0.001 R = 0.236; p = 0.010 NS
E conjugation degree [%] NS NS NS
THF conjugation degree [%] R = 0.242; p = 0.019 R = 0.246; p = 0.013 NS
THE conjugation degree [%] R = 0.233; p = 0.019 NS NS

Each time, a semi-partial correlation (R) and a p-value were noted. The associations where the sole predictor of the response variable was the hypertensive disorder of pregnancy are marked in bold

UFF urinary free cortisol, UFE urinary free cortisone, THF tetrahydrocortisol, THE tetrahydrocortisone, alloTHF allo-tetrahydrocortisol, alloTHE allo-tetrahydrocortisone, NS not significant