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. 2018 Jun 6;10:655–669. doi: 10.2147/CLEP.S156210

Table 3.

Maternal sociodemographic, lifestyle, and health-related characteristics of the postnatal sample with psychiatric disorders according to antidepressant exposure during pregnancy (n=173)

Antidepressant in pregnancy
No, n=87 Yes, n=86
Pregnancy characteristics
Weeks since childbirth, n (%)
 0–12 22 (25.3) 16 (18.6)
 13–24 14 (16.1) 13 (15.1)
 ≥25 51 (58.6) 57 (66.3)
No previous children, n (%) 42 (48.3) 39 (45.4)
No perinatal use of folate,a n (%) 5 (5.8) 7 (8.1)
Completely unplanned pregnancy, n (%) 16 (18.4) 15 (17.4)
Sociodemographic characteristics
Residence, n (%)
 Western Europe 27 (31.0) 30 (34.9)
 Northern Europe 31 (35.6) 51 (59.3)
 Eastern Europe 29 (33.3) 5 (5.8)
Maternal age (years; range 15–50), mean (SD) 29.0 (6.7) 31.7 (5.5)
Marital status, no (%)
 Married/cohabiting 72 (82.8) 78 (90.7)
 Other than above 15 (17.2) 8 (9.3)
Working status at conception, n (%)
 Employed 42 (48.3) 48 (55.8)
 Student 19 (61.3) 12 (38.7)
 Homemaker 15 (17.2) 12 (14.0)
 Job seeker/others 11 (12.6) 14 (16.3)
Educational attainment, n (%)
 Below high school 17 (19.5) 11 (12.8)
 High school 39 (44.8) 33 (45.8)
 Above high school 31 (42.5) 42 (48.8)
Immigrant status (yes),b n (%) 3 (3.5) 4 (4.7)
Lifestyle characteristics
Alcohol use during pregnancy (yes),c n (%) 19 (21.8) 14 (16.3)
Smoking during pregnancy (yes), n (%) 16 (18.4) 13 (15.1)
Neurotic personality traits (range 8–40),d mean (SD) 28.8 (5.4) 28.2 (5.2)
Health-related characteristics
Medical contact due to fertility problems (yes), n (%) 15 (17.2) 14 (16.3)
Nausea in pregnancy (yes), n (%) 66 (75.9) 68 (79.1)
Sleeping problems in pregnancy (yes), n (%) 54 (62.1) 50 (58.1)
Chronic somatic comorbidity (yes),e n (%) 64 (73.6) 43 (50.0)
Comedication in pregnancy
Anxiolytics and sedatives 8 (9.2) 16 (18.6)
Antipsychotics 7 (8.1) 9 (10.5)
Antiepileptics 4 (4.6) 6 (7.0)
Acetaminophen 49 (56.3) 71 (82.6)

Notes: Missing values were <1.5% for immigrant status, employment, unplanned pregnancy, smoking, fertility problems, folate use, and alcohol use and between 2.5% and 3.0% for neuroticism traits.

a

Indicates use of folate before and/or during pregnancy;

b

women having the first language different from the official main language in the country of residence;

c

indicates alcohol consumption after awareness of the pregnancy;

d

measured via the Big Five Inventory personality scale;

e

defined as self-reported asthma, allergy, hypothyroidism, epilepsy, diabetes (type I or II), and rheumatic or cardiovascular diseases.

Abbreviation: SD, standard deviation.