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. 2018 Apr 18;13(3):214–227. doi: 10.1080/15592294.2016.1229730

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

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Figure 9. — Univariate Kaplan-Meier survival analysis of combined high SFRP3 and WNT1 mRNA expression indicated a favorable prognosis for adenocarcinoma patients. (A) Kaplan-Meier survival analysis based on the TCGA human lung dataset illustrates no prognostic value for the proto-oncogene WNT1. (B) Univariate Kaplan-Meier analysis of adenocarcinoma patients with low WNT1 mRNA expression shows no prognostic benefit provided by SFRP3 mRNA expression. (C) Univariate survival analysis reveals a better prognostic outcome for adenocarcinoma patients with high WNT1 and high SFRP3 mRNA expression. Patients were dichotomized by high WNT1 mRNA expression (median > 2.52) and low WNT1 expression (median ≤ 2.52). Red line: higher SFRP3 mRNA expression (median > 272.11); black line: moderate SFRP3 expression (median ≤ 272.11). Vertical lines: censored cases.