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. 2018 May 10;13(3):318–330. doi: 10.1080/15592294.2018.1451720

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Figure 3. — Differences in gene expression between AMC (n = 3) and control (n = 3) PND9 hypothalami. (A) Principal components analysis (PCA) of the top 500 most variably expressed genes. Outlines represent 95% confidence intervals. (B) Scatter plot DE transcripts with the top DE transcripts labeled. Grey indicates no significant difference in expression, while red indicates a significant (q < 0.05) difference. (C) Hierarchal clustering analysis (HCA) of significant (q < 0.05) DE transcripts. (D) Significant (q < 0.05) enriched gene ontologies and pathways from significantly (q < 0.05) DE transcripts. (E) Most significant (q < 0.0001) transcription factor binding site identified by motif enrichment analysis.