Figure 2.

Effects of different concentrations of Doxorubicin on the mRNA expression of Notch pathway members.

Notes: (A) HeLa S3 cells were treated with Doxorubicin (0, 300, 900 and 1200 μM) for 24 hours. The mRNA expression levels of Notch pathway components and targets were examined by real-time RT-PCR. (B) Selective representation of Doxorubicin-responsive Notch pathway genes. GAPDH was used as an internal control for the normalization of gene expression.

Abbreviation: RT-PCR, reverse transcriptase polymerase chain reaction.