Table 4.
Summary of data collected from case reports included in the literature review
| Variable | n |
|---|---|
| Age, years | |
| Mean | 52.4 |
| Range | 1–84 |
| Gender | |
| Male | 13 |
| Female | 28 |
| Etiology | |
| Pure malignant solid tumor | 31 |
| Malignant solid tumor with hematopathy | |
| Thalassemia | 1 |
| Hemolytic anemia | 2 |
| Sickle cell anemia | 1 |
| Myelofibrosis | 6 |
| Thrombotic thrombocytopenic purpura | 1 |
| Others | 1 |
| Physical examination | |
| Hepatomegaly | 3 |
| Splenomegaly | 6 |
| Hepatomegaly and splenomegaly | 4 |
| Imaging examination | |
| X-ray photography | 9 |
| Ultrasound | 11 |
| Computed tomography | 20 |
| MRI | 5 |
| 18F-FDG PET | 3 |
| Acquisition of pathologic tissue | |
| Excision | 25 |
| Biopsy | 14 |
| Autopsy | 3 |
| Histopathologic component | |
| Pure EMH | 29 |
| Mixed EMH | 13 |
| Bone marrow biopsy | |
| Associated with hematopathy | 6 |
| Normal bone marrow | 4 |
| Therapy method | |
| Surgery | 25 |
| Hydroxyurea | 1 |
| Blood transfusions | 2 |
| Observation | 14 |
| Outcome | |
| Stable disease | 10 |
| Died of malignancy | 6 |
Note: Mixed EMH is that the EMH was present in the tumor tissues.
Abbreviations: EMH, extramedullary hematopoiesis; 18F-FDG PET, 18F-fluoro-2-deoxy-d-glucose positron emission tomography; MRI, magnetic resonance imaging.