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. 2018 Jun 12;13(6):e0198797. doi: 10.1371/journal.pone.0198797

Table 7. Diagnostic cluster combining history elements and physical examination tests to exclude partial or complete ACL tears (n = 43).

Clusters Se (95% CI) Sp (95% CI) NPV (95% CI) LR- (95% CI)
Knee complaints are unlikely due to a partial or complete ACL tear in individuals with: 0.93 (0.81–0.99) 0.87 (0.82–0.91) 0.99 (0.96–1.00) 0.08 (0.03–0.24)
➢ Negative history of pivot or “popping” sensation during trauma
        AND
➢ Negative Lachman or pivot shift test
Internal validation 0.91 (0.78–0.97) 0.85 (0.80–0.89) 0.98 (0.95–0.99) 0.11 (0.04–0.27)

Se: sensitivity; Sp: specificity; NPV: negative predictive value; LR-: negative likelihood ratio. Clusters are obtained using recursive partitioning with all variables associated with the diagnosis of an ACL tear. Internal validation was assessed by bootstrapping (n = 1000).