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. Author manuscript; available in PMC: 2018 Jun 12.
Published in final edited form as: J Clin Psychopharmacol. 2018 Feb;38(1):34–41. doi: 10.1097/JCP.0000000000000829

Table 3.

Estimated Effect Sizes (Risk Ratios) of Varenicline Dose on 7-day PPA Smoking Abstinence Outcomes at Three Time Points According to Different Models

Model Risk Ratio 95% CI P-value
3-month
Unadjusted (no imputation or matching) 2.3 1.4–3.6 <0.001
Adjusted with imputation and no matching 2.1 1.1–3.7 0.016
Unadjusted with imputation and matching 2.3 1.2–4.1 0.008
Adjusted with imputation and matching 2.9 1.1–4.7 0.004
6-month
Unadjusted (no imputation or matching) 2.6 1.6–3.9 <0.001
Adjusted with imputation and no matching 2.5 1.4–4.1 <0.001
Unadjusted with imputation and matching 2.4 1.3–4.3 0.008
Adjusted with imputation and matching 2.5 1.1–5.2 0.02
9-month
Unadjusted (no imputation or matching) 2.2 1.4–3.3 <0.001
Adjusted with imputation and no matching 2.5 1.1–3.9 <0.001
Unadjusted with imputation and matching 2.3 1.3–3.9 0.003
Adjusted with imputation and matching 2.7 1.2–5.2 0.008

Abbreviations: 7-day PPA, 7-day point prevalence abstinence. CI, confidence interval.