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. 2018 Apr 12;10(4):e2469. doi: 10.7759/cureus.2469

Table 2. Summary of infective endocarditis treatment and outcome.

CVA: Cerebrovascular accident; LVOT: Left ventricular outflow tract; PPM: Permanent pacemaker.

First author (year) [Ref. No.] Vegetation size on echocardiography CVA severity Medical treatment (Y/N) Penicillin resistance (Y/N) Surgical intervention (Y/N) Required valve replacement Outcome
Htoo Kyaw (2016) [11] Vegetation on anterior and posterior mitral valve leaflets Aphasia and right-sided hemiplegia Y N Y Y Recovered
Hossein Schandiz (2015)[20] Massive vegetation on mitral valve Not mentioned: presented as syncope N Y N (planned) N Died before surgery
Manova David (2015) [10] 7 mm on anterior leaflets and 15 mm on posterior leaflet of mitral valve Dysarthria and left-sided hemiparesis Y N Y Y Recovered
Jose Kuzhively (2014) [9] 15.5 x 11.1 mm on the anterior leaflet of the mitral valve Right hemiplegia and facial palsy Y N N N Recovered
Wei-Chi Tsai (2013) [15] Aortic valve vegetation with perivalvular abscess Right internuclear ophthalmoplegia Y N N (planned) N Died before surgery
Federico Pacei (2013) [6] Not mentioned Quadriplegia Y N N N Recovered
Rosaria Pecoraro (2012) [5] 10.3 x 16.6 mm on anterior mitral valve leaflet Right leg weakness Y N Y Y Recovered
Kalliopi-Stavroula Chatzigeorgiou (2010)[21] 18 x 22 mm at LVOT/7 x 16 mm on PPM leads and small vegetation on tricuspid valve Dysarthria and facial nerve paresis Y/Y N/N Y/N (only removal of PPM wires) N/N Recovered (died 5 years later with calciphylaxis)/Recovered
Asmaa Tamdy (2010)[14] 17 x 5 mm on the anterior mitral valve with small vegetation on both leaflets of mitral valve Right hemiplegia and aphasia Y N N (planned) N (planned) Died before surgery
Yeun Tarl Fresner Ng Jao (2010) [16] Not mentioned Right hemiparesis Y N Y Y Died
Khaled E. Alebrahim (2007) [17] 7 x 8 mm on anterior and 3 x 6 mm posterior leaflets of mitral valve Right hemiparesis and aphasia Y N Y Y Recovered
S. Gianella (2006) [7] 12 x 4 mm on the bicuspid aortic valve Right hemiparesis and aphasia Y N Y Y Recovered
M Rodríguez-Gascón (2003) [18] 3 x 3 cm vegetation on mitral valve Left hemiparesis Y N N N Recovered
A. Sánchez (2000) [19] Not mentioned Generalized weakness Y N Y Y Recovered
Susan J. Burgert (1999) [8] 5 mm perforation with multiple vegetations on aortic valve Dysarthria, aphasia and right hemiparesis Y N Y Y Recovered
T. W. Koh (1996) [12] Vegetation on posterior leaflets of the mitral valve Dysphasia and right facial weakness Y N Y Y Recovered
B Walsh and JP Mounsey ( 1990) [13] Not mentioned Right-hand weakness Y N Y Y Recovered