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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Lancet Gastroenterol Hepatol. 2018 May 3;3(7):477–488. doi: 10.1016/S2468-1253(18)30096-7

Figure 2.

Figure 2

Associations between the EDP and the HSS domains and EREFS features. Spearman correlation analysis between the gene levels on the EDP and HSS domains (left) and the EREFS features (right), using the absolute value to account for differences in the direction of the effect across genes. Statistical significance was calculated with the Kruskal-Wallis test and Dunn’s post-hoc test. *p<0·0001 vs EA, ESL, DEC, DIS, SEA and LPF. †p<0·05 vs edema, exudates, rings and stricture. EDP=EoE diagnostic panel. EoE=eosinophilic esophagitis. HSS=EoE histology scoring system. EREFS=EoE endoscopic reference score. EI=eosinophilic inflammation. BZH=basal zone hyperplasia. EA=eosinophilic abscess. ESL=eosinophilic surface layering. DIS=dilated intercellular spaces. SEA=surface epithelial alteration. DEC=dyskeratotic epithelial cells. LPF=lamina propria fibers.