Fig. 3.

Serial OCT scans from four different patients undergoing aflibercept treatment injections. 1a Shows IRF prior to commencing aflibercept having undergone 25 previous bevacizumab/ranibizumab injections. 1b is 6 months post-switch, 1c is at 12 months and 1d is at 18 months showing stabilisation after initial resolution. 2a Shows SRF and cystic IRF pre-switch with seven previous bevacizumab injections and 2b shows complete resolution of both SRF and IRF at 6 months. 3a Shows IRF and SRF having had three previous bevacizumab injections and 3b at 6 months post-aflibercept. 4a Shows IRF with an ERM pre-switch having undergone six previous ranibizumab injections and 4b showing resolution of IRF, but with continued blunting of the foveal contour at 6 months. IRF intraretinal fluid, SRF subretinal fluid, ERM epiretinal membrane