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. 2018 Apr;15(4):275–283. doi: 10.11909/j.issn.1671-5411.2018.04.011

Table 3. Tests of change in antihypertensive prescribing, blood pressure and pulse over nine months.

Variables Change between baseline and month four
Change between month four and month nine
Intervention Control Intervention Control
*Antihypertensive drugs, IRR (95% CI) 0.8 (0.7–0.9) 0.9 (0.9–1.0) 0.9 (0.9–1.0) 0.9 (0.8–1.0)
#High blood pressure, IRR (95% CI) 1.0 (0.9–1.2) 0.7 (0.5–1.0) 1.0 (0.9–1.2) 1.1 (0.5–2.5)
Cognitive status, IRR (95% CI)
Severe dementia 1 1 1 1
Moderate dementia 1.1 (1.0–1.4) 1.0 (0.9–1.2) 1.0 (0.8–1.2) 1.1 (0.8–1.3)
Mild dementia 1.0 (0.8–1.3) 1.0 (0.9–1.2) 1.1 (0.8–1.7) 1.1 (0.8–1.4)
No dementia 1.2 (1.0–1.5) 1.0 (0.9–1.2) 1.1 (0.9–1.4) 0.7 (0.4–1.3)
§Systolic blood pressure, beta (95% CI)
No antihypertensives described, n = 93 –2 (–6.3 to 2.6) 2 (–2.9 to 6.4) 2
Antihypertensives deprescribed, n = 43 14 (7.7–21.2) –8 (–15.2 to –1.2) –8
¤Pulse, beta (95% CI)
No antihypertensives described, n = 93 0 (–2.7–3.5) 0 (–3.1 to 3.5)
Antihypertensives deprescribed, n = 43 2 (–2.9–6.5) 0 (–5.4 to 4.4)

*Multilevel Poisson regression with IRR representing change in antihypertensive drug use; #Multilevel Poisson regression with IRR representing change in antihypertensive drug use for patients with high blood pressure compared to low/normal blood pressure; Multilevel Poisson regression with IRR representing change in antihypertensive drug use between the different levels of cognitive function at baseline; §Multilevel linear regression with betas representing change in blood pressure between baseline and month four; ¤Multilevel linear regression with betas representing change in pulse between baseline and month four. IRR: incidence rate ratios.