Table 3. Tests of change in antihypertensive prescribing, blood pressure and pulse over nine months.
Variables | Change between baseline and month four |
Change between month four and month nine |
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Intervention | Control | Intervention | Control | ||||||||||
*Antihypertensive drugs, IRR (95% CI) | 0.8 (0.7–0.9) | 0.9 (0.9–1.0) | 0.9 (0.9–1.0) | 0.9 (0.8–1.0) | |||||||||
#High blood pressure, IRR (95% CI) | 1.0 (0.9–1.2) | 0.7 (0.5–1.0) | 1.0 (0.9–1.2) | 1.1 (0.5–2.5) | |||||||||
†Cognitive status, IRR (95% CI) | |||||||||||||
Severe dementia | 1 | 1 | 1 | 1 | |||||||||
Moderate dementia | 1.1 (1.0–1.4) | 1.0 (0.9–1.2) | 1.0 (0.8–1.2) | 1.1 (0.8–1.3) | |||||||||
Mild dementia | 1.0 (0.8–1.3) | 1.0 (0.9–1.2) | 1.1 (0.8–1.7) | 1.1 (0.8–1.4) | |||||||||
No dementia | 1.2 (1.0–1.5) | 1.0 (0.9–1.2) | 1.1 (0.9–1.4) | 0.7 (0.4–1.3) | |||||||||
§Systolic blood pressure, beta (95% CI) | |||||||||||||
No antihypertensives described, n = 93 | –2 (–6.3 to 2.6) | 2 (–2.9 to 6.4) | 2 | ||||||||||
Antihypertensives deprescribed, n = 43 | 14 (7.7–21.2) | –8 (–15.2 to –1.2) | –8 | ||||||||||
¤Pulse, beta (95% CI) | |||||||||||||
No antihypertensives described, n = 93 | 0 (–2.7–3.5) | 0 (–3.1 to 3.5) | |||||||||||
Antihypertensives deprescribed, n = 43 | 2 (–2.9–6.5) | 0 (–5.4 to 4.4) |
*Multilevel Poisson regression with IRR representing change in antihypertensive drug use; #Multilevel Poisson regression with IRR representing change in antihypertensive drug use for patients with high blood pressure compared to low/normal blood pressure; †Multilevel Poisson regression with IRR representing change in antihypertensive drug use between the different levels of cognitive function at baseline; §Multilevel linear regression with betas representing change in blood pressure between baseline and month four; ¤Multilevel linear regression with betas representing change in pulse between baseline and month four. IRR: incidence rate ratios.