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. 2018 Jun 12;8:8930. doi: 10.1038/s41598-018-27208-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Experimental design of animal model used for Small and Large MFP experiments (B) On day 0, the number of discrete signal voids, representing iron-labeled cells, that arrested in the brain on day 0 as well as brain BLI signal was not significantly different between mice with and without a small MFP tumour. (C) There were also no significant differences in cell arrest for mice with large MFP tumours. (D,E) All four groups of mice were not significantly different from each other in MRI cell arrest at day 0 as well as BLI signal in the brain at day 0. Data is presented as mean +/− SD.