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Minimum inhibitory concentration of 2-aminoimidazole molecules against other C. difficile strains compared to vancomycin.
| C. difficile strain | MIC (μg/mL) |
|||
|---|---|---|---|---|
| Compound 1 | Compound 2 | Compound 3 | Vancomycin | |
| CD196 | 5 | 5 | 5 | 0.31 |
| M68 | 5 | 10 | 10 | 0.31 |
| CF5 | 5 | 5 | 10 | 0.31 |
| 630 | 5 | 5 | 5 | 0.31 |
| BI9 | 2.5–5 | 5 | 5 | 0.16 |
| M120 | 5 | 10 | 10 | 0.31 |
Minimum inhibitory concentration (MIC) was determined by broth microdilution as per modified CLSI guidelines for anaerobes. Data represent mean values from triplicate trials.
