Figure 1. H&E staining of stomach in the four groups.

Rats were killed and then their stomachs were cut along the greater curvature. Paraffin sections were prepared from the pyloric area and subjected to H&E staining (scale bar: 20 μm). The vehicle group: the gastric mucosa dysplasia was severe, the gland structure was irregularly arranged, and the pathological mitotic phenomenon existed. The XZ-1 and Retin-A group: unobvious gastric mucosal gland hyperplasia and mild inflammation were observed. n=15 per group.