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| Group | n | Moderate dysplasia | Severe dysplasia | Incidence of dysplasia |
|---|---|---|---|---|
| Vehicle | 15 | 5 | 8 | 86.7% |
| XZ-1 | 15 | 3 | 3 | 40.0% |
| XZ-1 + PDTC | 15 | 3 | 6 | 60.0%* |
| XZ-1 + PFT | 15 | 4 | 6 | 66.7%* |
Rats in the vehicle, XZ-1, XZ-1 + PDTC, and XZ-1 + PFT group received treatment as described in ‘Materials and methods’ section.
P<0.05 compared with XZ-1 group.
