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. 2018 Jun 6;9:540. doi: 10.3389/fphar.2018.00540

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Copyright © 2018 Cai, Hou, Zhao, Liu, He, Liu, Hua, Li, Huang, Ou, Luo and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Puerarin decreased proliferation of cultured NRCF. The CCK-8 assay was used to detect proliferation of NRCF. (A) Effects of various concentrations of AngII (0.1–10 μM) on proliferation of NRCF. (B) Effects of various concentrations of puerarin (10–1000 μM) on AngII-induced proliferation of NRCF. ^∗∗P < 0.01 vs. control, ^#P < 0.05 vs. AngII, ^##P < 0.01 vs. AngII. n = 8 for each group.