Table 1.
Effect of Caesalpinia sappan L. leaf (L) and heartwood (H) extracts prepared in chloroform, methanol and water on MCF-7 (Human breast cancer) and A549 (Human lung cancer) cells, Camptothecin is taken as positive control.
| Cell line | Plant sample | Camptothecin (50 uM) | 50 µg/ml | 150 µg/ml | 250 µg/ml | 350 µg/ml | 450 µg/ml |
|---|---|---|---|---|---|---|---|
| A549 Cell line | L CHCL3 | 57.48±0.03 | 87.2±0.03 | 86.37±0.01 | 83.41±0.02 | 71.56±0.04 | 67.07±0.00 |
| LH2O | 57.48±0.03 | 86.87±0.13 | 84.14±0.02 | 92.55±0.03 | 94.77±0.01 | 97.48±0.00 | |
| L MET | 57.48±0.03 | 101.52±0.00 | 89.50±0.01 | 89.34±0.07 | 86.00±0.04 | 84.23±0.02 | |
| H H2O | 57.48±0.03 | 81.06±0.29 | 87.69±0.00 | 88.35±0.00 | 88.06±0.03 | 96.82±0.06 | |
| H Met | 57.48±0.03 | 100.12±0.00 | 80.69±0.01 | 78.14±0.06 | 78.02±0.07 | 60.12±0.07 | |
| MCF7 Cell line | L CHCL3 | 56.32±0.02 | 98.84±0.07 | 102.17±0.01 | 108.63±0.06 | 112.24±0.01 | 102.64±0.01 |
| LH2O | 56.32±0.02 | 105.10±0.00 | 104.76±0.00 | 102.24±0.02 | 97.82±0.03 | 96.39±0.14 | |
| L MET | 56.32±0.02 | 107.68±0.01 | 96.33±0.05 | 85.54±0.19 | 63.96±0.05 | 46.19±0.00 | |
| H H2O | 56.32±0.02 | 107.00±0.00 | 93.12±0.01 | 62.51±0.01 | 37.89±0.02 | 12.04±0.00 | |
| H Met | 56.32±0.02 | 101.15±0.01 | 52.31±0.00 | 4.01±0.00 | 2.31±0.00 | 1.22±0.01 |