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. 2018 May 21;19:868–877. doi: 10.1016/j.dib.2018.05.050
Subject area Biology
More specific subject area Screening for Anti Cancer Activity in medicinal plants and Ethno medicines
Type of data Tables, microscopy images, text file, graphs, Chromatogram figure, docking images
How data was acquired Conducting of anticancer activity assays and cytotoxicity studies with methanol and water extracts of leaf and heartwood of Caesalpinia sappan L. on MCF-7 (Human breast cancer) and A549 (Human lung cancer) cell lines. The in vitro anti tumor activity was screened by assessing tumor volume, viable and nonviable tumor cell count, tumor weight, hematological parameters and biochemical estimations by MTT Assay and Flow cytometry studies.
Data format Analyzed data
Experimental factors Leaf and heart wood was extracted in chloroform, water and methanol solvents to study their cytotoxic effect on human cancer cell lines and determine the extracts IC50 value.
Experimental features The effect of leaf and heartwood extracts prepared in water and methanol on MCF-7 (Human breast cancer) and A549 (Human lung cancer) and Identification of compounds from Caesalpinia sappan L., leaf and heartwood water and methanol extracts through LC–MS () and Docking studies against a BCl2 (B-cell lymphoma 2) protein which regulates the apoptosis.
Data source location Yogi Vemana University campus green house facility (N 14°.473′, E 78°.710)
Data accessibility Data are available within this article