Fig. 3.

K40 and G313fs abolish ANGPTL4 effect on triglycerides. a Plasma triglycerides levels (4 h fasted) in C57Bl/6 mice before (Baseline) and 7 days after (Day 7) hydrodynamic delivery via tail vein injection of cDNA encoding human E40, K40, and Gly313fs ANGPTL4 variants. Control animals were injected with empty vector. b ANGPTL4 plasma levels were measured in the animals described in (a). All groups had five animals. Values are mean ± SEM. Statistics performed by two-way ANOVA with Bonferroni correction, ****p < 0.0001 vs control